Specification
Tests | Specifications | Results |
Characters | White to off-white crystalline powder with a characteristic sulfide-like order | Complies |
Identification | IR:similar to Reference Standard | Complies |
Specific Rotation | -127°to -132° | -131° |
Loss on Drying | ≤0.5% | 0.06% |
Sulphated Ash | ≤0.2% | 0.03% |
Heavy metals | ≤0.002% | Complies |
pH | 2.0 to 2.6 | 2.3 |
Related Compouds | 1.Single Impurity ≤1.0% 2.Sum of Impurity≤2.0% | Undetected Undetected |
Assay(Anhydrous) | 98.0% to 101.5% | 99.8% |
Introduction
Name:Loperamide hydrochloride
Formula:C29H33ClN2O2.HCl
Molecular Weight:513.55
Synonyms: Imodium;1-Piperidinebutanamide,4-(4-chlorophenyl)-4- hydroxy-N,N-dimethyl-R,R-diphenyl-
,monohydrochloride;Imodium (TN);Lopemin;Prestwick_302;4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-N,N-
dimethyl-2,2-diphenyl-butanamide hydrochloride;R 18553; Loperamide hydrochloride (JAN/USP);
Loperamide HCl;
EINECS: 252-082-4
Melting Point: 223-225 °C
Boiling Point: 647.2 °C at 760 mmHg
Flash Point: 345.2 °C
Appearance: White powder
Loperamide hydrochloride is a white or almost white crystalline powder, can be used as antidiarrheal, or long-acting anti-diarrheal drug, used for treating acute and chronic dysentery. When overdose may occur drowsiness, constipation, muscle tension, restlessness, bradycardia and other respiratory symptoms, naloxone detoxification available, and patients were observed for at least 48 hours in order to detect inhibition of the central nervous system.
Main Function
Antidiarrheal drugs. Various causes for the symptoms of acute and chronic diarrhea. Ileum for ostomy patients can reduce the volume and frequency of defecation, stool thick to increase hardness.
Application
1. patients with diarrhea, especially children, frequent loss of water and electrolytes, replenish water and electrolytes is the most important therapeutic measures, children should the FDA under the guidance of a doctor.
2. for acute diarrhea, such as 48 hours after using this service, no improvement in clinical symptoms, should stop using, it is recommended to consult a doctor.
3. liver dysfunction may lead to drug overdose relative, should pay attention to the central nervous system symptoms of toxic reactions.
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment
Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR
Henan Kaixiang biological Technology Co., Ltd., was established in July 2017. It is a professional animal and plant extracts modern and advanced enterprise object, pharmaceutical intermediates, and natural active ingredients. In the development, production and marketing, is very powerful.
Headquartered in Henan. It has a research and development center and the Analysis and Testing Center, with strong comprehensive national strength. The company has 200 acres of experimental field of plant cultivation, extraction, distillation, rectification, chromatography, three specialized production lines, as well as 10,000 square meters of GMP standard workshop. A variety of production equipment more than 200 sets of experiments. US company to introduce the company WATERS LC-MS chromatograph and a 8453 UV-Vis spectrophotometerand Switzerland TLC scanner (HPTLC) and other advanced detection equipment to ensure the quality of our products are oriented to international standards Advanced equipment and professional and technical personnel, we are standing in front of the industry foundation, we thought to provide quality products and services to target customers around the word .
Kaixiang is the best choice of global customers .
1.We enjoy high reputation for years of sincerity business,have thousands of customers from all over the world.
2.We have advanced test equipments and production line of international standard to ensure the stability for our products quality.
3.Kai xiang Learning Organization has trained a group of professional staff,which are full of energy,ambitious,innovation.our outstanding team solve the technology and products as well as various of issues with their professional and passion.
4.Via the world wide internet,we can get many information of products demand and then to achieve the scale of supply.it also means which save the purchase cost and get mutual success.
5.Clients need our best concern,the rich experience of service for more than 32 countries and 3200 clients have guaranteed our products timely and safety arrive.
6.Reliable quality and excellent service is our commitment to every customers.we firmly believe our customer’s success is our success.at Kaixiang, we are always committed to giving our customers the reliable products and services that they expect and deserve.
1.Any inquiries will be replied with in 12 hours.
2.Dedication to quatity,supply& service.
3.Strictly on selecting raw meterials.
4.Reasonable & competitive price ,fast lead time.
5.Smple order in stock and one week for bulk production.
6. We have strong cooperation with FEDEX,TNT,DHL,EMS,or you also can choose your own shipping agent.